SERUM SICKNESS IN RABBITS
نویسندگان
چکیده
منابع مشابه
Serum Sickness in Rabbits
1. The injection of a single large dose of normal horse serum into rabbits results in the appearance 3 to 8 days later of erythematous and edematous reactions on the ears in 68.9 per cent of the animals. 2. The injections may be given by any of several routes and reactions appear when the site of injection is definitely distant from the ears. 3. Injections of various antisera into rabbits cause...
متن کاملSerum Sickness in Rabbits I. Manifestations of Serum Sickness
The occurrence in man of reactions subsequent to a first injection of certain foreign proteins has long been recognized and, following the general use of antisera of various types, these reactions were thoroughly studied by von Pirquet and Schick (1) who gave the name serum sickness or serum disease to this phenomenon. I t was possible to study it quite extensively as it occurs in man. However,...
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Diving acclimatization refers to a reduced susceptibility to acute decompression sickness (DCS) in individuals undergoing repeated compression-decompression cycles. We demonstrated in a previous study that the mechanism responsible for this acclimatization is similar to that of stress preconditioning. In this study, we investigated the protective effect of prior DCS preconditioning on the sever...
متن کاملComparative Histologic and Immunologic Studies in Rabbits of Induced Hypersensitivity of the Serum Sickness Type
A histologic and quantitative immunologic study was made on a large group of rabbits injected intravenously with a single dose of crystallized bovine albumin and bled and sacrificed at various intervals after injection. Both cardiovascular and renal lesions were encountered in high incidence. The various stages in the development of these lesions were observed from their first appearance until ...
متن کاملA Comparative Histologic and Immunologic Study in Rabbits of Induced Hypersensitivity of the Serum Sickness Type*
The histologic changes in animals made hypersensitive to foreign protein have been extensively studied. Klinge (1) and Vaubel (2) were among the first to describe lesions attributable to hypersensitivity and they noted the similarity of these lesions to those of rheumatic fever and polyarteritis nodosa. Later, Rich and Gregory (3-6) amply confirmed and extended these observations. The demonstra...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1931
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.54.4.597